Mir-2-o55

MirGeneDB ID

Sme-Mir-2-o55

Family name

MIR-2 (all species)

Seed

UCAUCAA

Species

Freshwater planarian (Schmidtea mediterranea)

MiRBase ID

sme-mir-2c

Paralogues

Sme-Mir-2-o51a Sme-Mir-2-o51b Sme-Mir-2-o52 Sme-Mir-2-o53 Sme-Mir-2-o54 Sme-Mir-2-o56 Sme-Mir-2-o57 Sme-Mir-2-o58

Orthologues

Node of Origin (locus)

S. mediterranea

Node of Origin (family)

Protostomia

Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)

NNSW01000006_dd_Smes_g4_6: 2195588-2195642 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-2-o55)

Mir-71-P18 NNSW01000006_dd_Smes_g4_6: 2195478-2195544 [+] UCSC Ensembl
Mir-2-o55 NNSW01000006_dd_Smes_g4_6: 2195588-2195642 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

AUCGUCAUUAUUUCUUUUUCAAAUACAAAAAUCAUCAAUUUGGUCUGUUAUAAAUGGCUUUUAUCACAGCCAAAACUGAUGAUCUUAUAAAUUUGUCAAACAUCCCAAUUUAGCA

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Structure

        10         20        30          40        50       
AUCGUCAUUAUUUCUUUUU-     ACAAAA-       A-|    U    U   AAUG 
                    CAAAU       AUCAUCA  UUUGG CUGU AUA    \
                    GUUUA       UAGUAGU  AAACC GACA UAU    G
ACGAUUUAACCCUACAAACU     AAUAUUC       CA^    -    C   UUUC 
   110       100        90        80        70         60

Deep sequencing

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Comment

It is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes are classified as orphans pending further data and analysis.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Se	Se	Se	Se	Se	Se	Se	Se	Se	Se	Se	Se	Ne	Wh	Wh	Wh

Mature sequence

Sme-Mir-2-o55_5p

mirBase accession

MIMAT0012094

Sequence

0- AUCAUCAAUUUGGUCUGUUAUA -22

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Star sequence

Sme-Mir-2-o55_3p*

mirBase accession

MIMAT0003967

Sequence

33- UCACAGCCAAAACUGAUGAUCU -55

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