Mir-2-o58

MirGeneDB ID

Sme-Mir-2-o58

Family name

MIR-2 (all species)

Seed

CAUCAUU

Species

Freshwater planarian (Schmidtea mediterranea)

MiRBase ID

sme-mir-2b

Paralogues

Sme-Mir-2-o51a Sme-Mir-2-o51b Sme-Mir-2-o52 Sme-Mir-2-o53 Sme-Mir-2-o54 Sme-Mir-2-o55 Sme-Mir-2-o56 Sme-Mir-2-o57

Orthologues

Node of Origin (locus)

S. mediterranea

Node of Origin (family)

Protostomia

Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)

NNSW01000014_dd_Smes_g4_14: 3096425-3096480 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

GUUAGUUGAAUAUUUUUAUGGUUAUUGCUUUCAUCAUUGUUGGUUGUCAGUUAUUGUAUUCAAUAUCACAGCCAAUUUUGAUGAGAUGAGAUAGCUUUCAGUCGUCACAAUUUUUC

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Structure

        10         20         30        40        50       
GUUAGUUGAAUAUUUUUAU-       GC-|       UU         CAGUUAUUG 
                    GGUUAUU   UUUCAUCA  GUUGGUUGU         U
                    UCGAUAG   AGAGUAGU  UAACCGACA         A
CUUUUUAACACUGCUGACUU       AGU^       UU         CUAUAACUU 
    110       100        90        80        70        60

Deep sequencing

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Comment

It is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes are classified as orphans pending further data and analysis.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Se	Se	Se	Se	Se	Se	Se	Se	Se	Se	Se	Se	Ne	Wh	Wh	Wh

Mature sequence

Sme-Mir-2-o58_5p

mirBase accession

MIMAT0003965

Sequence

0- UCAUCAUUGUUGGUUGUCAGU -21

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Co-mature sequence

Sme-Mir-2-o58_3p

mirBase accession

MIMAT0003966

Sequence

35- UCACAGCCAAUUUUGAUGAGA -56

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