Let-7-P2c1

MirGeneDB ID

Tgu-Let-7-P2c1

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Zebra finch (Taeniopygia guttata)

MiRBase ID

tgu-let-7d

Paralogues

Tgu-Let-7-P1c Tgu-Let-7-P1d Tgu-Let-7-P2a1 Tgu-Let-7-P2a2 Tgu-Let-7-P2a3 Tgu-Let-7-P2a4 Tgu-Let-7-P2b1 Tgu-Let-7-P2b2 Tgu-Let-7-P2b4 Tgu-Let-7-P2c2 Tgu-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2c1 Ami-Let-7-P2c1 Bge-Let-7 Bpl-Let-7 Bta-Let-7-P2c1 Cfa-Let-7-P2c1 Cgi-Let-7 Cli-Let-7-P2c1 Cmi-Let-7-P2c1 Cpi-Let-7-P2c1 Cpo-Let-7-P2c1 Cte-Let-7 Dan-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2c1 Dpu-Let-7 Dsi-Let-7 Dya-Let-7 Esc-Let-7 Ete-Let-7-P2c1 Gga-Let-7-P2c1 Gja-Let-7-P2c1 Hme-Let-7 Hsa-Let-7-P2c1 Isc-Let-7 Lan-Let-7 Lch-Let-7-P2c1 Lgi-Let-7 Loc-Let-7-P2c1 Mdo-Let-7-P2c1 Mml-Let-7-P2c1 Mmu-Let-7-P2c1 Mun-Let-7-P2c1 Npo-Let-7 Oan-Let-7-P2c1 Obi-Let-7 Ocu-Let-7-P2c1 Ovu-Let-7 Pbv-Let-7-P2c1 Pfl-Let-7 Pmi-Let-7 Rno-Let-7-P2c1 Sha-Let-7-P2c1 Sko-Let-7 Spt-Let-7-P2c1 Spu-Let-7 Sto-Let-7-P2c1 Tca-Let-7 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(TaeGut1_add)

12: 19654532-19654606 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2c1)

Mir-2987 12: 19651218-19651275 [-] UCSC Ensembl
Let-7-P2c1 12: 19654532-19654606 [-] UCSC Ensembl
Let-7-P2b1 12: 19655525-19655601 [-] UCSC Ensembl
Let-7-P2a1 12: 19655935-19656006 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CUGCACAGAGGAAGCGUGGGGCUCCUAGGAAGAGGUAGUAGGUUGCAUAGUUUUAGGGCAGGGAUUUUGCUCAGAAGGAGGUAACUAUACAACCUGCUGCCUUUCUUAGGGCUUUAUUAUAACACCAGGACCUUU

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Structure

        10           20        30        40        50        60       
CUGCACAGAGGAAGCGU---|    U       A              C      UUAGGGCAGGGAUU 
                    GGGGC CCUAGGA GAGGUAGUAGGUUG AUAGUU              U
                    UUUCG GGAUUCU UUCCGUCGUCCAAC UAUCAA              U
UUUCCAGGACCACAAUAUUA^    -       -              A      UGGAGGAAGACUCG 
   130       120        110        100        90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Fe	Fe	Fe	Fe	Ma	Ma	Ma	Ma

Mature sequence

Tgu-Let-7-P2c1_5p

mirBase accession

MIMAT0014536

Sequence

0- AGAGGUAGUAGGUUGCAUAGUU -22

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Star sequence

Tgu-Let-7-P2c1_3p*

mirBase accession

MIMAT0026992

Sequence

54- CUAUACAACCUGCUGCCUUUC -75

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