Mir-19-P2a

MirGeneDB ID

Hsa-Mir-19-P2a

Family name

MIR-19 (all species)

Seed

GUGCAAA

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-19b-1

Paralogues

Hsa-Mir-19-P1a Hsa-Mir-19-P2c

Orthologues

Aca-Mir-19-P2a Ami-Mir-19-P2a Bta-Mir-19-P2a Cfa-Mir-19-P2a Cli-Mir-19-P2a Cmi-Mir-19-P2a Cpi-Mir-19-P2a Cpo-Mir-19-P2a Dno-Mir-19-P2a Dre-Mir-19-P2a1 Dre-Mir-19-P2a2 Ete-Mir-19-P2a Gga-Mir-19-P2a Gja-Mir-19-P2a Gmo-Mir-19-P2a1 Gmo-Mir-19-P2a2 Lch-Mir-19-P2a Loc-Mir-19-P2a Mal-Mir-19-P2a1 Mal-Mir-19-P2a2 Mdo-Mir-19-P2a Mml-Mir-19-P2a Mmu-Mir-19-P2a Mun-Mir-19-P2a Oan-Mir-19-P2a5 Oan-Mir-19-P2a6 Ocu-Mir-19-P2a Pbv-Mir-19-P2a Rno-Mir-19-P2a Sha-Mir-19-P2a Spt-Mir-19-P2a Sto-Mir-19-P2a Tgu-Mir-19-P2a Tni-Mir-19-P2a1 Tni-Mir-19-P2a2 Xla-Mir-19-P2a3 Xla-Mir-19-P2a4 Xtr-Mir-19-P2a

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(hg38)

chr13: 91351207-91351267 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-19-P2a)

Mir-17-P1a chr13: 91350618-91350677 [+] UCSC Ensembl
Mir-17-P2a chr13: 91350756-91350820 [+] UCSC Ensembl
Mir-19-P1a chr13: 91350904-91350961 [+] UCSC Ensembl
Mir-17-P4a chr13: 91351072-91351130 [+] UCSC Ensembl
Mir-19-P2a chr13: 91351207-91351267 [+] UCSC Ensembl
Mir-92-P1a chr13: 91351324-91351382 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UGUCCUGUUACUGAACACUGUUCUAUGGUUAGUUUUGCAGGUUUGCAUCCAGCUGUGUGAUAUUCUGCUGUGCAAAUCCAUGCAAAACUGACUGUGGUAGUGAAAAGUCUGUAGAAAAGUA

Get precursor sequence

Structure

        10            20        30         40         50          
UGUCCUGUUACUGAACA----|  UU                 -  -      UC    UGUGUG 
                     CUG  CUAUGGUUAGUUUUGCA GG UUUGCA  CAGC      \
                     GAU  GGUGUCAGUCAAAACGU CC AAACGU  GUCG      A
AUGAAAAGAUGUCUGAAAAGU^  --                 A  U      --    UCUUAU 
 .       110       100          90        80          70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

UGUG in loop

Tissue expression

Ad	Ar	Bl	Bo	Bo	Bo	Bo	Bo	Br	Br	Br	Br	Br	Br	Br	Br	Br	Br	Br	Es	Ga	He	He	He	He	He	Ki	Li	Lu	Ly	Mu	Ne	Pa	Pl	Pl	Sk	Sp	Sp	St	Su	Te	Th	To	Tr	Ve

Star sequence

Hsa-Mir-19-P2a_5p*

mirBase accession

MIMAT0004491

Sequence

0- AGUUUUGCAGGUUUGCAUCCAGC -23

Get sequence

Proposed targets

microrna.org: MIMAT0004491
TargetScanVert: hsa-miR-19b-1-5p
TargetMiner: hsa-miR-19b-1-5p
miRDB: MIMAT0004491

Mature sequence

Hsa-Mir-19-P2a_3p

mirBase accession

MIMAT0000074

Sequence

38- UGUGCAAAUCCAUGCAAAACUGA -61

Get sequence

Proposed targets

microrna.org: MIMAT0000074
TargetScanVert: hsa-miR-19b-3p
TargetMiner: hsa-miR-19b-3p
miRDB: MIMAT0000074