Let-7-P2b2

MirGeneDB ID

Rno-Let-7-P2b2

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-let-7b

Paralogues

Rno-Let-7-P1b Rno-Let-7-P1c Rno-Let-7-P1d Rno-Let-7-P2a1 Rno-Let-7-P2a2 Rno-Let-7-P2a3 Rno-Let-7-P2b1 Rno-Let-7-P2b3 Rno-Let-7-P2c1 Rno-Let-7-P2c2 Rno-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2b2 Ami-Let-7-P2b2 Bge-Let-7 Bpl-Let-7 Bta-Let-7-P2b2 Cfa-Let-7-P2b2 Cgi-Let-7 Cli-Let-7-P2b2 Cmi-Let-7-P2b2 Cpi-Let-7-P2b2 Cpo-Let-7-P2b2 Cte-Let-7 Dan-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2b2 Dpu-Let-7 Dre-Let-7-P2b2a Dre-Let-7-P2b2b Dsi-Let-7 Dya-Let-7 Esc-Let-7 Ete-Let-7-P2b2 Gga-Let-7-P2b2 Gja-Let-7-P2b2 Gmo-Let-7-P2b2a Hme-Let-7 Hsa-Let-7-P2b2 Isc-Let-7 Lan-Let-7 Lch-Let-7-P2b2 Lgi-Let-7 Loc-Let-7-P2b2 Mal-Let-7-P2b2a Mal-Let-7-P2b2b Mdo-Let-7-P2b2 Mml-Let-7-P2b2 Mmu-Let-7-P2b2 Mun-Let-7-P2b2 Npo-Let-7 Oan-Let-7-P2b2 Obi-Let-7 Ocu-Let-7-P2b2 Ovu-Let-7 Pbv-Let-7-P2b2 Pfl-Let-7 Pmi-Let-7 Sha-Let-7-P2b2 Sko-Let-7 Spt-Let-7-P2b2 Spu-Let-7 Sto-Let-7-P2b2 Tca-Let-7 Tgu-Let-7-P2b2 Tni-Let-7-P2b2a Tni-Let-7-P2b2b Xbo-Let-7 Xla-Let-7-P2b2c Xla-Let-7-P2b2d Xtr-Let-7-P2b2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(rn6)

chr7: 126590633-126590707 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2b2)

Let-7-P2a2 chr7: 126590225-126590293 [+] UCSC Ensembl
Let-7-P2b2 chr7: 126590633-126590707 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

GGCCUCCUCCAGAAUGUGGACACCGCGGGGUGAGGUAGUAGGUUGUGUGGUUUCAGGGCAGUGAUGUCGCCCCUCCGAAGAUAACUAUACAACCUACUGCCUUCCCUGAGGCGCCCAGGGACACGUCCACAUGGA

Get precursor sequence

Structure

        10          20        30        40        50        60       
GGCCUCCUCCAGAAUGU--| ACA  G     U                     UCAGGGCAGUGAUG 
                   GG   CC CGGGG GAGGUAGUAGGUUGUGUGGUU              U
                   CC   GG GUCCC UUCCGUCAUCCAACAUAUCAA              C
AGGUACACCUGCACAGGGA^ CGC  A     -                     UAGAAGCCUCCCCG 
   130       120       110        100        90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

UG at 5p(-14)

Tissue expression

Ad	Ad	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Dr	Dr	Du	Du	Du	Du	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Li	Li	Li	Li	Me	Me	Mu	Mu	Mu	Mu	Mu	Mu	Mu	Mu	Ov	Pa	Pa	St	St	St	Te	Ut	Wh	Br	Fa	He	Ki	La	Li	Li	Lu	Mu	Pa	Sk	Sm	Sp	St	Te	Th

Mature sequence

Rno-Let-7-P2b2_5p

mirBase accession

MIMAT0000775

Sequence

0- UGAGGUAGUAGGUUGUGUGGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000775
TargetScanVert: rno-let-7b-5p
miRDB: MIMAT0000775

Star sequence

Rno-Let-7-P2b2_3p*

mirBase accession

MIMAT0004705

Sequence

54- CUAUACAACCUACUGCCUUCC -75

Get sequence

Proposed targets

microrna.org: MIMAT0004705
TargetScanVert: rno-let-7b-3p
miRDB: MIMAT0004705