Mir-219-P2

MirGeneDB ID

Hsa-Mir-219-P2

Family name

MIR-219 (all species)

Seed

GAUUGUC

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-219a-2

Paralogues

Hsa-Mir-219-P2-as Hsa-Mir-219-P3

Orthologues

Aae-Mir-219 Aca-Mir-219-P2 Ami-Mir-219-P2 Bfl-Mir-219 Bge-Mir-219 Bla-Mir-219 Bta-Mir-219-P2 Bta-Mir-219-P2-as Cfa-Mir-219-P2 Cfa-Mir-219-P2-as Cgi-Mir-219 Cin-Mir-219 Cli-Mir-219-P2 Cmi-Mir-219-P2 Cpi-Mir-219-P2 Cpo-Mir-219-P2 Cpo-Mir-219-P2-as Csc-Mir-219 Cte-Mir-219 Dan-Mir-219 Dma-Mir-219 Dme-Mir-219 Dmo-Mir-219 Dno-Mir-219-P2 Dno-Mir-219-P2-as Dpu-Mir-219 Dre-Mir-219-P2a Dre-Mir-219-P2b Dsi-Mir-219 Dya-Mir-219 Esc-Mir-219 Ete-Mir-219-P2 Gga-Mir-219-P2 Gja-Mir-219-P2 Gmo-Mir-219-P2a Isc-Mir-219 Lan-Mir-219 Lch-Mir-219-P2 Loc-Mir-219-P2 Mal-Mir-219-P2a Mal-Mir-219-P2b Mdo-Mir-219-P2 Mml-Mir-219-P2 Mml-Mir-219-P2-as Mmu-Mir-219-P2 Mmu-Mir-219-P2-as Mun-Mir-219-P2 Oan-Mir-219-P2 Obi-Mir-219 Ocu-Mir-219-P2 Ocu-Mir-219-P2-as Ovu-Mir-219 Pbv-Mir-219-P2 Pfl-Mir-219 Pma-Mir-219-o2 Pmi-Mir-219 Rno-Mir-219-P2 Rno-Mir-219-P2-as Sha-Mir-219-P2 Sko-Mir-219 Spt-Mir-219-P2 Spu-Mir-219 Sto-Mir-219-P2 Tca-Mir-219 Tgu-Mir-219-P2 Tni-Mir-219-P2a Tni-Mir-219-P2b Xbo-Mir-219 Xla-Mir-219-P2c Xla-Mir-219-P2d Xtr-Mir-219-P2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(hg38)

chr9: 128392632-128392696 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-219-P2)

Mir-219-P2 chr9: 128392632-128392696 [-] UCSC Ensembl
Mir-219-P2-as chr9: 128392634-128392698 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CCAGGGCCCUGAACUCAGGGGCUUCGCCACUGAUUGUCCAAACGCAAUUCUUGUACGAGUCUGCGGCCAACCGAGAAUUGUGGCUGGACAUCUGUGGCUGAGCUCCGGGCGCAACAGGGGCGGGG

Get precursor sequence

Structure

        10          20        30        40        50        60  
CCAGGGCCCUGAACUCA--|      C     U   U     AA           UACGAGUC 
                   GGGGCUU GCCAC GAU GUCCA  CGCAAUUCUUG        U
                   CCUCGAG CGGUG CUA CAGGU  GUGUUAAGAGC        G
GGGGCGGGGACAACGCGGG^      U     U   -     CG           CAACCGGC 
   120       110       100        90         80        70

Deep sequencing

Go to detailed chart

Comment

The MIR-219 family shows substantial variation of arm-usage and is currently, across all species, considered a co-mature.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Ad	Ar	Bl	Bo	Bo	Bo	Bo	Bo	Br	Br	Br	Br	Br	Br	Br	Br	Br	Br	Br	Es	Ga	He	He	He	He	He	Ki	Li	Lu	Ly	Mu	Ne	Pa	Pl	Pl	Sk	Sp	Sp	St	Su	Te	Th	To	Tr	Ve

Mature sequence

Hsa-Mir-219-P2_5p

mirBase accession

MIMAT0000276

Sequence

0- UGAUUGUCCAAACGCAAUUCUUG -23

Get sequence

Proposed targets

microrna.org: MIMAT0000276
TargetScanVert: hsa-miR-219a-5p
miRDB: MIMAT0000276

Co-mature sequence

Hsa-Mir-219-P2_3p

mirBase accession

MIMAT0004675

Sequence

43- AGAAUUGUGGCUGGACAUCUGU -65

Get sequence

Proposed targets

microrna.org: MIMAT0004675
TargetScanVert: hsa-miR-219a-2-3p
miRDB: MIMAT0004675